Human BTN1A1/Butyrophilin protein (Recombinant) (C-His) (STJP002604)

SKU:
STJP002604

Current Stock:
Host: HEK293 cells
Reactivity: Human
Note: STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Short Description: Recombinant-Human BTN1A1/Butyrophilin-C-His protein was developed from hek293 cells and has a target region of C-His. For use in research applications.
Formulation: Lyophilized from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction: Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Immunoreactivity: Measured by its ability to inhibit Anti-CD3-induced proliferation of jurkat cells. The ED50 for this effect is 3.35-13.4 ng/mL.
Gene Symbol: BTN1A1
Gene ID: 696
Uniprot ID: BT1A1_HUMAN
Immunogen Region: Ala27-Arg242
Immunogen: Recombinant Human BTN1A1/Butyrophilin Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Ala 27-Arg 242) of human BTN1A1/Butyrophilin (Accession #NP_001723.2) fused with a 6×His tag at the C-terminus
Function May function in the secretion of milk-fat droplets. May act as a specific membrane-associated receptor for the association of cytoplasmic droplets with the apical plasma membrane. Inhibits the proliferation of CD4 and CD8 T-cells activated by anti-CD3 antibodies, T-cell metabolism and IL2 and IFNG secretion.
Protein Name Butyrophilin Subfamily 1 Member A1
Bt
Database Links Reactome: R-HSA-8851680
Cellular Localisation Membrane
Single-Pass Type I Membrane Protein
Secreted
Alternative Protein Names Butyrophilin Subfamily 1 Member A1 protein
Bt protein
BTN1A1 protein
BTN protein

Information sourced from Uniprot.org

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