Human BTF3 protein (Recombinant) (His-Tag) (STJP017977)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human BTF3-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.25 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% Glycerol, 2mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | BTF3 |
| Gene ID | 689 |
| Uniprot ID | BTF3_HUMAN |
| Accession Number | NP_001032726 |
| Immunogen | Human |
| Immunogen Region | 1-206aa |
| Immunogen Sequence |
Additional Info
| Function | When associated with NACA, prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. BTF3 is also a general transcription factor that can form a stable complex with RNA polymerase II. Required for the initiation of transcription. |
| Protein Name | Transcription Factor Btf3Nascent Polypeptide-Associated Complex Subunit BetaNac-BetaRna Polymerase B Transcription Factor 3 |
| Database Links | |
| Cellular Localisation | CytoplasmNucleusThe Heterodimer With Naca Is Cytoplasmic |
| Alternative Protein Names | Transcription Factor Btf3 proteinNascent Polypeptide-Associated Complex Subunit Beta proteinNac-Beta proteinRna Polymerase B Transcription Factor 3 proteinBTF3 proteinNACB proteinOK proteinSW-cl.8 protein |
Information sourced from Uniprot.org