Human BRK1 protein (Recombinant) (His-Tag) (STJP018613)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human BRK1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 20% Glycerol, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | BRK1 |
| Gene ID | 55845 |
| Uniprot ID | BRK1_HUMAN |
| Accession Number | NP_060932 |
| Immunogen | Human |
| Immunogen Region | 1-75aa |
| Immunogen Sequence |
Additional Info
| Function | Involved in regulation of actin and microtubule organization. Part of a WAVE complex that activates the Arp2/3 complex. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes. |
| Protein Name | Protein Brick1Brk1 |
| Database Links | Reactome: R-HSA-2029482Reactome: R-HSA-4420097Reactome: R-HSA-5663213Reactome: R-HSA-9013149Reactome: R-HSA-9013404Reactome: R-HSA-9013423Reactome: R-HSA-9664422 |
| Cellular Localisation | CytoplasmCytoskeleton |
| Alternative Protein Names | Protein Brick1 proteinBrk1 proteinBRK1 proteinC3orf10 proteinHSPC300 proteinMDS027 protein |
Information sourced from Uniprot.org