Human BRDG1/STAP1 protein (Recombinant) (His-Tag) (STJP017662)

SPECIFICATIONS
HostE.coli
ImmunogenHuman
STJP017662
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General Information

Short DescriptionRecombinant-Human BRDG1/STAP1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration0.5 mg/mL
FormulationLiquid in 20mM Tris-HCl buffer (pH 8.0) containing 30% Glycerol, 0.1M NaCl, 1mM DTT
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolSTAP1
Gene ID26228
Uniprot IDSTAP1_HUMAN
Accession NumberNP_036240
ImmunogenHuman
Immunogen Region1-295aa
Immunogen SequenceMMAKKP PKPAPRRIFQ ERLKITALPL YFEGFLLIKR SGYREYEHYW TELRGTTLFF YTDKKSIIYV DKLDIVDLTC LTEQNSTEKN CAKFTLVLPK EEVQLKTENT ESGEEWRGFI LTVTELSVPQ NVSLLPGQVI KLHEVLEREK KRRIETEQST SVEKEKEPTE DYVDVLNPMP ACFYTVSRKE ATEMLQKNPS LGNMIL

Additional Info

Post Translational Modifications Phosphorylated on tyrosine by TEC. Phosphorylated on tyrosine by KIT.
Function In BCR signaling, appears to function as a docking protein acting downstream of TEC and participates in a positive feedback loop by increasing the activity of TEC.
Protein Name Signal-Transducing Adaptor Protein 1
Stap-1
Bcr Downstream-Signaling Protein 1
Docking Protein Brdg1
Stem Cell Adaptor Protein 1
Database Links
Cellular Localisation Nucleus
Cytoplasm
Mitochondrion
Alternative Protein Names Signal-Transducing Adaptor Protein 1 protein
Stap-1 protein
Bcr Downstream-Signaling Protein 1 protein
Docking Protein Brdg1 protein
Stem Cell Adaptor Protein 1 protein
STAP1 protein
BRDG1 protein

Information sourced from Uniprot.org

Citations

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