Human BPNT1 protein (Recombinant) (N-His) (STJP010801)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human BPNT1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | BPNT1 |
| Gene ID | 10380 |
| Uniprot ID | BPNT1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Pro308 |
Additional Info
| Function | Phosphatase that converts 3'(2')-phosphoadenosine 5'-phosphate (PAP) to AMP and inositol 1,4-bisphosphate (Ins(1,4)P2) to inositol 4-phosphate. Is also able to hydrolyze adenosine 3'-phosphate 5'-phosphosulfate (PAPS) to adenosine 5'-phosphosulfate (APS). Probably prevents the toxic accumulation of PAP, a compound which inhibits a variety of proteins, including PAPS-utilizing enzymes such as sulfotransferases, and RNA processing enzymes. Could also play a role in inositol recycling and phosphoinositide metabolism. Is not active on 3'-AMP, inositol-1-phosphate and inositol-1,4,5-triphosphate. |
| Protein Name | 3'(2' -5'-Bisphosphate Nucleotidase 13'-Phosphoadenosine 5'-Phosphate PhosphatasePap PhosphataseBisphosphate 3'-Nucleotidase 1Bpntase 1HspipInositol-Polyphosphate 1-Phosphatase |
| Database Links | Reactome: R-HSA-156584 |
| Cellular Localisation | |
| Alternative Protein Names | 3'(2' -5'-Bisphosphate Nucleotidase 1 protein3'-Phosphoadenosine 5'-Phosphate Phosphatase proteinPap Phosphatase proteinBisphosphate 3'-Nucleotidase 1 proteinBpntase 1 proteinHspip proteinInositol-Polyphosphate 1-Phosphatase proteinBPNT1 protein |
Information sourced from Uniprot.org