Human BPGM protein (Recombinant) (C-His) (STJP014377)
SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human BPGM-C-His protein was developed from e.coli and has a target region of C-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Supplied as a 0.22 Mu m filtered solution in 20mM Tris-HCl, 1mM DTT, pH 8.0. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8ยฐC for one week. Store at-20 to-80ยฐC for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/ยตg as determined by LAL test. |
Target Information
| Gene Symbol | BPGM |
| Gene ID | 669 |
| Uniprot ID | PMGE_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ser2-Lys259 |
Additional Info
| Post Translational Modifications | Glycation of Lys-159 in diabetic patients inactivates the enzyme. |
| Function | Plays a major role in regulating hemoglobin oxygen affinity by controlling the levels of its allosteric effector 2,3-bisphosphoglycerate (2,3-BPG). Also exhibits mutase activity. |
| Protein Name | Bisphosphoglycerate MutaseBpgm2 -3-Bisphosphoglycerate Mutase - Erythrocyte2 -3-Bisphosphoglycerate Synthase2 -3-Diphosphoglycerate MutaseDpgmBpg-Dependent Pgam |
| Database Links | Reactome: R-HSA-70171 |
| Cellular Localisation | |
| Alternative Protein Names | Bisphosphoglycerate Mutase proteinBpgm protein2 -3-Bisphosphoglycerate Mutase - Erythrocyte protein2 -3-Bisphosphoglycerate Synthase protein2 -3-Diphosphoglycerate Mutase proteinDpgm proteinBpg-Dependent Pgam proteinBPGM protein |
Information sourced from Uniprot.org