Human BLOC1S6 protein (Recombinant) (N-His-SUMO & C-Strep) (STJP007435)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human BLOC1S6-N-His-SUMO & C-Strep protein was developed from e.coli for the region N-His-SUMO & C-Strep. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | BLOC1S6 |
| Gene ID | 26258 |
| Uniprot ID | BL1S6_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Asp46-Met172 |
Additional Info
| Post Translational Modifications | Phosphorylated. |
| Function | Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. May play a role in intracellular vesicle trafficking, particularly in the vesicle-docking and fusion process. |
| Protein Name | Biogenesis Of Lysosome-Related Organelles Complex 1 Subunit 6Bloc-1 Subunit 6Pallid Protein HomologPallidinSyntaxin 13-Interacting Protein |
| Database Links | Reactome: R-HSA-432722 |
| Cellular Localisation | CytoplasmMembranePeripheral Membrane ProteinIt Can Exist As A Soluble Protein As Well As A Peripheral Membrane Protein |
| Alternative Protein Names | Biogenesis Of Lysosome-Related Organelles Complex 1 Subunit 6 proteinBloc-1 Subunit 6 proteinPallid Protein Homolog proteinPallidin proteinSyntaxin 13-Interacting Protein proteinBLOC1S6 proteinPA proteinPLDN protein |
Information sourced from Uniprot.org