Human Biglycan/BGN protein (Recombinant) (C-His) (STJP000916)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Human Biglycan/BGN Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Asp38-Lys368) of human Biglycan/BGN (Accession #NP_001702.1) fused with a 6×His tag at the C-terminus.
General Information
| Short Description | Recombinant-Human Biglycan/BGN-C-His protein was developed in hek293 cells using the region Asp38-Lys368. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Determination Method | < 0.1 EU/Mu g of the protein by LAL method. |
Target Information
| Gene Symbol | BGN |
| Gene ID | 633 |
| Uniprot ID | PGS1_HUMAN |
| Immunogen | Recombinant Human Biglycan/BGN Protein is produced by HEK293 expression system. The target protein is expressed with sequence (Asp38-Lys368) of human Biglycan/BGN (Accession #NP_001702.1) fused with a 6×His tag at the C-terminus. |
| Immunogen Region | Asp38-Lys368 |
| Immunogen Sequence | DEEASGADTSGVLDPDSVTP TYSAMCPFGCHCHLRVVQCS DLGLKSVPKEISPDTTLLDL QNNDISELRKDDFKGLQHLY ALVLVNNKISKIHEKAFSPL RKLQKLYISKNHLVEIPPNL PSSLVELRIHDNRIRKVPKG VFSGLRNMNCIEMGGNPLEN SGFEPGAFDGLKLNYLRISE AKLTGIPKDLPETLNELHLD HNKIQAIELEDLLRYSKLYR LGLGHNQIRMIENGSLSFL |
Additional Info
| Tissue Specificity | Detected in placenta (at protein level). Found in several connective tissues, especially in articular cartilages. |
| Post Translational Modifications | The two attached glycosaminoglycan chains can be either chondroitin sulfate or dermatan sulfate. |
| Function | May be involved in collagen fiber assembly. |
| Protein Name | BiglycanBone/Cartilage Proteoglycan IPg-S1 |
| Database Links | Reactome: R-HSA-1971475Reactome: R-HSA-2022870Reactome: R-HSA-2022923Reactome: R-HSA-2024101Reactome: R-HSA-3000178Reactome: R-HSA-3560783Reactome: R-HSA-3560801Reactome: R-HSA-3595172Reactome: R-HSA-3595174Reactome: R-HSA-3595177Reactome: R-HSA-4420332 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Protein Names | Biglycan proteinBone/Cartilage Proteoglycan I proteinPg-S1 proteinBGN proteinSLRR1A protein |
Information sourced from Uniprot.org