Human BHMT protein (Recombinant) (His-Tag) (STJP019571)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human BHMT-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 7.5) containing 20% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | BHMT |
| Gene ID | 635 |
| Uniprot ID | BHMT1_HUMAN |
| Accession Number | NP_001704.2 |
| Immunogen | Human |
| Immunogen Region | 1-406aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Found exclusively in liver and kidney. |
| Function | Involved in the regulation of homocysteine metabolism. Converts betaine and homocysteine to dimethylglycine and methionine, respectively. This reaction is also required for the irreversible oxidation of choline. |
| Protein Name | Betaine--Homocysteine S-Methyltransferase 1 |
| Database Links | Reactome: R-HSA-1614635Reactome: R-HSA-6798163 |
| Cellular Localisation | CytoplasmCytosolNucleusPredominantly Localized In The Cytoplasm With A Small Fraction Detected In The NucleusTranslocates Into The Nucleus Upon Oxidative Stress |
| Alternative Protein Names | Betaine--Homocysteine S-Methyltransferase 1 proteinBHMT protein |
Information sourced from Uniprot.org