Human BHLHB8 (Basic Helix Loop Helix Domain Containing Protein B8) Sandwich ELISA Kit (STJE0007473)
SPECIFICATIONS
General Information
| Short Description | This BHLHB8 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.071ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | BHLHA15 |
| Gene ID | 168620 |
| Uniprot ID | BHA15_HUMAN |
| Sample Type | tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | Expressed in brain, liver, spleen and skeletal muscle. |
| Post Translational Modifications | |
| Function | Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E-box occupancy by homodimers. May also negatively regulate bHLH-mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E-box consensus sequence 5'-CANNTG-3'. |
| Protein Name | Class A Basic Helix-Loop-Helix Protein 15Bhlha15Class B Basic Helix-Loop-Helix Protein 8Bhlhb8Muscle - Intestine And Stomach Expression 1Mist-1 |
| Database Links | Reactome: R-HSA-9925561 |
| Cellular Localisation | Nucleus |
| Alternative ELISA Names | Class A Basic Helix-Loop-Helix Protein 15 ELISA kitBhlha15 ELISA kitClass B Basic Helix-Loop-Helix Protein 8 ELISA kitBhlhb8 ELISA kitMuscle - Intestine And Stomach Expression 1 ELISA kitMist-1 ELISA kitBHLHA15 ELISA kitBHLHB8 ELISA kitMIST1 ELISA kit |
| output |
Information sourced from Uniprot.org