Human BGN protein (Recombinant-Active) (C-His) (STJP011920)
SPECIFICATIONS
HostMammalian Cells
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Active-Human BGN-C-His protein was developed from mammalian cells and has a target region of C-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | Mammalian Cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | <0.1 EU/Mu g of the protein by the LAL method. |
| Immunoreactivity | Measured by its ability to inhibit the cell growth of mouse embryonic fibroblast adipose-like cells (mouse 3T3‑L1). The ED50 for this effect is 1.5-6 Mu g/mL. |
Target Information
| Gene Symbol | BGN |
| Gene ID | 633 |
| Uniprot ID | PGS1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Asp38-Lys368 |
Additional Info
| Post Translational Modifications | The two attached glycosaminoglycan chains can be either chondroitin sulfate or dermatan sulfate. |
| Function | May be involved in collagen fiber assembly. |
| Protein Name | BiglycanBone/Cartilage Proteoglycan IPg-S1 |
| Database Links | Reactome: R-HSA-1971475Reactome: R-HSA-2022870Reactome: R-HSA-2022923Reactome: R-HSA-2024101Reactome: R-HSA-3000178Reactome: R-HSA-3560783Reactome: R-HSA-3560801Reactome: R-HSA-3595172Reactome: R-HSA-3595174Reactome: R-HSA-3595177Reactome: R-HSA-4420332 |
| Cellular Localisation | SecretedExtracellular SpaceExtracellular Matrix |
| Alternative Protein Names | Biglycan proteinBone/Cartilage Proteoglycan I proteinPg-S1 proteinBGN proteinSLRR1A protein |
Information sourced from Uniprot.org