Human BEX3 protein (Recombinant) (N-His-KSI) (STJP015878)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human BEX3-N-His-KSI protein was developed from e.coli for the region N-His-KSI. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for further information. |
Target Information
| Gene Symbol | BEX3 |
| Gene ID | 27018 |
| Uniprot ID | BEX3_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ala2-Pro111 |
Additional Info
| Post Translational Modifications | Ubiquitinated. Degraded by the proteasome. |
| Function | May be a signaling adapter molecule involved in NGFR/p75NTR-mediated apoptosis induced by NGF. Plays a role in zinc-triggered neuronal death. In absence of reductive stress, acts as a pseudosubstrate for the CRL2(FEM1B) complex: associates with FEM1B via zinc, thereby preventing association between FEM1B and its substrates. |
| Protein Name | Protein Bex3Brain-Expressed X-Linked Protein 3Nerve Growth Factor Receptor-Associated Protein 1Ovarian Granulosa Cell 13.0 Kda Protein Hgr74P75ntr-Associated Cell Death Executor |
| Database Links | Reactome: R-HSA-205025 |
| Cellular Localisation | NucleusCytoplasmCytosolShuttles Between The Cytoplasm And The NucleusAssociates With Replicating Mitochondria |
| Alternative Protein Names | Protein Bex3 proteinBrain-Expressed X-Linked Protein 3 proteinNerve Growth Factor Receptor-Associated Protein 1 proteinOvarian Granulosa Cell 13.0 Kda Protein Hgr74 proteinP75ntr-Associated Cell Death Executor proteinBEX3 proteinDXS6984E proteinNADE proteinNGFRAP1 protein |
Information sourced from Uniprot.org