Human Betacellulin/BTC protein (Recombinant) (C-hFc) (STJP002897)

Name: Human Betacellulin/BTC protein (Recombinant) (C-hFc) (STJP002897)
SKU: STJP002897
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostHEK293 cells

ConjugationUnconjugated

ImmunogenRecombinant Human Betacellulin/BTC Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Asp32-Tyr111) of human Betacellulin/BTC (Accession #NP_001720.1) fused with and a hFc tag at the C-terminus.

STJP002897

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General Information

Short Description	Recombinant-Human Betacellulin/BTC-C-hFc protein was developed in hek293 cells using the region Asp32-Tyr111. For use in research applications.
Host	HEK293 cells
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Conjugation	Unconjugated
Formulation	Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4.
Storage Instruction	Store at-20°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles.
Immunoreactivity	Measured in a cell proliferation assay using BALB/3T3 mouse fibroblasts. The ED₅₀ for this effect is 1.02-4.06 ng/mL, corresponding to a specific activity of 2.46×10⁵~9.80×10⁵ units/mg.
Determination Method	<0.1 EU/Mu g

Target Information

Gene Symbol	BTC
Gene ID	685
Uniprot ID	BTC_HUMAN
Immunogen	Recombinant Human Betacellulin/BTC Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Asp32-Tyr111) of human Betacellulin/BTC (Accession #NP_001720.1) fused with and a hFc tag at the C-terminus.
Immunogen Region	Asp32-Tyr111
Immunogen Sequence	DGNSTRSPETNGLLCGDPEE NCAATTTQSKRKGHFSRCPK QYKHYCIKGRCRFVVAEQTP SCVCDEGYIGARCERVDLFY

Additional Info

Function	Growth factor that binds to EGFR, ERBB4 and other EGF receptor family members. Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells.
Protein Name	Probetacellulin Cleaved Into - Betacellulin Btc
Database Links	Reactome: R-HSA-1227986 Reactome: R-HSA-1236394 Reactome: R-HSA-1250196 Reactome: R-HSA-1250342 Reactome: R-HSA-1250347 Reactome: R-HSA-1251985 Reactome: R-HSA-1257604 Reactome: R-HSA-177929 Reactome: R-HSA-179812 Reactome: R-HSA-180292 Reactome: R-HSA-180336 Reactome: R-HSA-182971 Reactome: R-HSA-1963640 Reactome: R-HSA-1963642 Reactome: R-HSA-212718 Reactome: R-HSA-2219530 Reactome: R-HSA-5638303 Reactome: R-HSA-5673001 Reactome: R-HSA-6785631 Reactome: R-HSA-6811558 Reactome: R-HSA-8847993 Reactome: R-HSA-8856825 Reactome: R-HSA-8856828 Reactome: R-HSA-8863795 Reactome: R-HSA-9009391 Reactome: R-HSA-9634638 Reactome: R-HSA-9664565 Reactome: R-HSA-9665686
Cellular Localisation	Betacellulin: Secreted Extracellular Space Probetacellulin: Cell Membrane Single-Pass Type I Membrane Protein
Alternative Protein Names	Probetacellulin Cleaved Into - Betacellulin protein Btc protein BTC protein

Information sourced from Uniprot.org

Citations

View product citations for antibody STJP002897 on CiteAb