Human beta-Sarcoglycan/SGCB protein (Recombinant) (His-Tag) (STJP019171)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human beta-Sarcoglycan/SGCB-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Denatured |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | SGCB |
| Gene ID | 6443 |
| Uniprot ID | SGCB_HUMAN |
| Accession Number | NP_000223 |
| Immunogen | Human |
| Immunogen Region | 87-318aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Highest expression in heart and skeletal muscle. Low expression in brain, kidney, placenta, pancreas and lung. High expression in fetal brain. Also found in fetal lung, kidney and liver. |
| Post Translational Modifications | Disulfide bonds are present. |
| Function | Component of the sarcoglycan complex, a subcomplex of the dystrophin-glycoprotein complex which forms a link between the F-actin cytoskeleton and the extracellular matrix. |
| Protein Name | Beta-SarcoglycanBeta-Sg43 Kda Dystrophin-Associated Glycoprotein43dagA3b |
| Database Links | Reactome: R-HSA-9913351 |
| Cellular Localisation | Cell MembraneSarcolemmaSingle-Pass Type Ii Membrane ProteinCytoplasmCytoskeleton |
| Alternative Protein Names | Beta-Sarcoglycan proteinBeta-Sg protein43 Kda Dystrophin-Associated Glycoprotein43dag proteinA3b proteinSGCB protein |
Information sourced from Uniprot.org