Human Beta-NGF/NGF/NGFB protein (Recombinant) (C-His) (STJP001960)
SPECIFICATIONS
HostHEK293 cells
ConjugationUnconjugated
ImmunogenRecombinant Human Beta-NGF/NGF/NGFB Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu19-Ala241) of human NGF (Accession #NP_002497.2) fused with and a 6ΓHis tag at the C-terminus.
General Information
| Short Description | Recombinant-Human Beta-NGF/NGF/NGFB-C-His protein was developed in hek293 cells using the region Glu19-Ala241. For use in research applications. |
| Host | HEK293 cells |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Lyophilised from a 0.22 Mu m filtered solution of PBS, pH 7.4. |
| Storage Instruction | Store at-20Β°C for up to 1 year from the date of receipt, and avoid repeat freeze-thaw cycles. |
| Immunoreactivity | Recombinant Human NGF stimulates cell proliferation of the TFβ1 human erythroleukemic cells. The ED50 for this effect is 2.2-8.6 ng/mL, corresponding to a specific activity of 1.16Γ105-4.55Γ105 units/mg. |
| Determination Method | <0.01 EU/Mu g |
Target Information
| Gene Symbol | NGF |
| Gene ID | 4803 |
| Uniprot ID | NGF_HUMAN |
| Immunogen | Recombinant Human Beta-NGF/NGF/NGFB Protein is produced by HEK293 cells expression system. The target protein is expressed with sequence (Glu19-Ala241) of human NGF (Accession #NP_002497.2) fused with and a 6ΓHis tag at the C-terminus. |
| Immunogen Region | Glu19-Ala241 |
| Immunogen Sequence | EPHSESNVPAGHTIPQAHWT KLQHSLDTALRRARSAPAAA IAARVAGQTRNITVDPRLFK KRRLRSPRVLFSTQPPREAA DTQDLDFEVGGAAPFNRTHR SKRSSSHPIFHRGEFSVCDS VSVWVGDKTTATDIKGKEVM VLGEVNINNSVFKQYFFETK CRDPNPVDSGCRGIDSKHWN SYCTTTHTFVKALTMDGKQA AWRFIRIDTACVCVLSRKAV RRA |
Additional Info
| Protein Name | Beta-Nerve Growth FactorBeta-Ngf |
| Database Links | Reactome: R-HSA-167021Reactome: R-HSA-167044Reactome: R-HSA-167060Reactome: R-HSA-170968Reactome: R-HSA-170984Reactome: R-HSA-177504Reactome: R-HSA-187042Reactome: R-HSA-187706Reactome: R-HSA-193648Reactome: R-HSA-193670Reactome: R-HSA-193681Reactome: R-HSA-198203Reactome: R-HSA-198745Reactome: R-HSA-205017Reactome: R-HSA-205025Reactome: R-HSA-205043Reactome: R-HSA-209543Reactome: R-HSA-209560Reactome: R-HSA-209563 |
| Cellular Localisation | SecretedEndosome LumenProngf Is Endocytosed After Binding To The Cell Surface Receptor Formed By Sort1 And Ngfr |
| Alternative Protein Names | Beta-Nerve Growth Factor proteinBeta-Ngf proteinNGF proteinNGFB protein |
Information sourced from Uniprot.org