Human beta 2 Microglobulin (beta 2 Microglobulin) Antibody Pair (STJAP00852)
General Information
| Short Description | This beta 2 Microglobulin antibody pair contains complimentary capture and detection antibodies, which work together under the principals of the. |
| Applications | ELISA |
| Host | Rabbit/Rabbit |
| Reactivity | Human |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Clonality | Monoclonal/Monoclonal |
| Clone ID | R09-9G-6/R01-1B-9 |
| Isotype | IgG |
| Conjugation | Unconjugated |
| Purification | Affinity Purification |
| Dilution Range | Determined by end user |
| Formulation | 0.01M PBS, pH 7.2 |
| Storage Instruction | Store at 4°C short term. Aliquot and store at-20°C long term. Avoid freeze/thaw cycles. |
Target Information
| Gene Symbol | B2M |
| Gene ID | 567 |
| Uniprot ID | B2MG_HUMAN |
| Immunogen | Recombinant protein |
Additional Info
| Post Translational Modifications | Glycation of Ile-21 is observed in long-term hemodialysis patients. |
| Function | Component of the class I major histocompatibility complex (MHC). Involved in the presentation of peptide antigens to the immune system. Exogenously applied M.tuberculosis EsxA or EsxA-EsxB (or EsxA expressed in host) binds B2M and decreases its export to the cell surface (total protein levels do not change), probably leading to defects in class I antigen presentation. |
| Protein Name | Beta-2-Microglobulin Cleaved Into - Beta-2-Microglobulin Form Pi 5.3 |
| Database Links | Reactome: R-HSA-1236974Reactome: R-HSA-1236977Reactome: R-HSA-164940Reactome: R-HSA-198933Reactome: R-HSA-2172127Reactome: R-HSA-2424491Reactome: R-HSA-6798695Reactome: R-HSA-877300Reactome: R-HSA-9637628Reactome: R-HSA-9705671Reactome: R-HSA-977225Reactome: R-HSA-983170 |
| Cellular Localisation | SecretedCell SurfaceDetected In Serum And Urine(Microbial Infection) In The Presence Of MTuberculosis Esxa-Esxb Complex Decreased Amounts Of B2m Are Found On The Cell Surface |
| Alternative Antibody Pair Names | Beta-2-Microglobulin Cleaved Into - Beta-2-Microglobulin Form Pi 5.3 antibody pairB2M antibody pairCDABP0092 antibody pairHDCMA22P antibody pair |
Information sourced from Uniprot.org
Citations
Product Review
Frequently Asked Questions
Common questions about Human beta 2 Microglobulin (beta 2 Microglobulin) Antibody Pair (STJAP00852)
This antibody pair is validated to detect human beta 2 Microglobulin (UniProt P61769). Reactivity has been confirmed for human samples only.
Both the capture and detection antibodies are rabbit monoclonal IgGs supplied unconjugated, with clone IDs R09-9G-6 and R01-1B-9 respectively. Both are affinity purified and formulated in 0.01M PBS at pH 7.2.
This antibody pair is validated for use in ELISA. No other assay formats are specified in the product documentation.
Working concentrations are determined by the end user and are not predefined in the product specification. Titration is recommended to establish optimal conditions for each laboratory setup.
Both antibodies should be stored at 4°C for short-term use. For long-term storage, aliquot and store at -20°C. Repeated freeze/thaw cycles should be avoided to maintain activity.
Both antibodies were generated using a recombinant protein immunogen. The specific immunogen region is not defined in the product documentation.
Orders typically arrive within 1 to 2 weeks, and often sooner depending on your location. If your timeline is critical, please contact us before ordering and we can advise on current lead times.
This product is shipped on gel ice packs to maintain integrity during transit. Priority shipping is used as standard to minimise time in transit.
A Certificate of Analysis (CoA) is provided with every order. If you do not receive one, please contact us and we will issue it promptly.