Human BEND6 protein (Recombinant) (His-Tag) (STJP018541)

SKU:
STJP018541
£134.50 - £738.50
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Short Description :Recombinant-Human BEND6-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications:SDS-PAGE
Host:E.coli
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Concentration:1 mg/mL
Formulation:Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 0.1M NaCl
Storage Instruction:For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.
Gene Symbol:BEND6
Gene ID:221336
Uniprot ID:BEND6_HUMAN
Accession Number:NP_689944
Immunogen:Human
Immunogen Region:1-279aa
Immunogen Sequence:MQKIVQT DEITNTQAFR KGKRKRTETM DSENANSDMD KGQRDPYSGN AFLPGESSSE DEEPLAELSK EELCAKIKSL KEKLTNTRKE NSRLRQSLVM LQVLPQAVTQ FEELVGMAEA LLKGGGTMST SASTLWRATN NSSPDSFAST CSNSNSNSSS PVSLKPEEEH QTDEKQFQIE KWQIARCNKS KPQKFINDLM QVLYTN
Function Acts as a corepressor of recombining binding protein suppressor hairless (RBPJ) and inhibits Notch signaling in neural stem cells, thereby opposing their self-renewal and promoting neurogenesis.
Protein Name Ben Domain-Containing Protein 6
Database Links
Cellular Localisation Nucleus
Alternative Protein Names Ben Domain-Containing Protein 6 protein
BEND6 protein
C6orf65 protein

Information sourced from Uniprot.org