Human BCMA/TNFRSF17 protein (Recombinant) (His-Tag) (STJP017949)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human BCMA/TNFRSF17-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | TNFRSF17 |
| Gene ID | 608 |
| Uniprot ID | TNR17_HUMAN |
| Accession Number | NP_001183 |
| Immunogen | Human |
| Immunogen Region | 78-184aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Expressed in mature B-cells, but not in T-cells or monocytes. |
| Function | Receptor for TNFSF13B/BLyS/BAFF and TNFSF13/APRIL. Promotes B-cell survival and plays a role in the regulation of humoral immunity. Activates NF-kappa-B and JNK. |
| Protein Name | Tumor Necrosis Factor Receptor Superfamily Member 17B-Cell Maturation ProteinCd Antigen Cd269 |
| Database Links | Reactome: R-HSA-5669034 |
| Cellular Localisation | Cell MembraneSingle-Pass Type Iii Membrane ProteinEndomembrane SystemPerinuclear Golgi-Like Structures |
| Alternative Protein Names | Tumor Necrosis Factor Receptor Superfamily Member 17 proteinB-Cell Maturation Protein proteinCd Antigen Cd269 proteinTNFRSF17 proteinBCM proteinBCMA protein |
Information sourced from Uniprot.org