Human BCAS2 protein (Recombinant) (N-T7 & C-His) (STJP014298)

SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
STJP014298-100
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General Information

Short DescriptionRecombinant-Human BCAS2-N-T7 & C-His protein was developed from e.coli and has a target region of N-T7 & C-His. For use in research applications.
ApplicationsELISA/WB
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

ConjugationUnconjugated
Dilution RangeReconstitute in sterile water for a stock solution.
FormulationLyophilized from a 0.22 Mu m filtered solution in 20mM Tris-HCl, 200mM NaCl, 2mM DTT, pH 8.0.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt.
Endotoxin< 1 EU/µg as determined by LAL test.

Target Information

Gene SymbolBCAS2
Gene ID10286
Uniprot IDSPF27_HUMAN
ImmunogenHomo sapiens (Human)
Immunogen RegionAla2-Phe225

Additional Info

Function Required for pre-mRNA splicing as component of the activated spliceosome. Component of the PRP19-CDC5L complex that forms an integral part of the spliceosome and is required for activating pre-mRNA splicing. May have a scaffolding role in the spliceosome assembly as it contacts all other components of the core complex. The PRP19-CDC5L complex may also play a role in the response to DNA damage (DDR).
Protein Name Pre-Mrna-Splicing Factor Spf27
Breast Carcinoma-Amplified Sequence 2
Dna Amplified In Mammary Carcinoma 1 Protein
Spliceosome-Associated Protein Spf 27
Database Links Reactome: R-HSA-72163
Cellular Localisation Nucleus
Nucleolus
Alternative Protein Names Pre-Mrna-Splicing Factor Spf27 protein
Breast Carcinoma-Amplified Sequence 2 protein
Dna Amplified In Mammary Carcinoma 1 Protein protein
Spliceosome-Associated Protein Spf 27 protein
BCAS2 protein
DAM1 protein

Information sourced from Uniprot.org

Citations

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