Human BART1/ARL2BP protein (Recombinant) (His-Tag) (STJP016905)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human BART1/ARL2BP-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 7.5) containing 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ARL2BP |
| Gene ID | 23568 |
| Uniprot ID | AR2BP_HUMAN |
| Accession Number | NP_036238 |
| Immunogen | Human |
| Immunogen Region | 1-163aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MDALEGESFA LSFSSASDAE FDAVVGYLED IIMDDEFQLL QRNFMDKYYL EFEDTEENKL IYTPIFNEYI SLVEKYIEEQ LLQRIPEFNM AAFTTTLQHH KDEVAGDIFD MLLTFTDFLA FKEMFLDYRA EKEGRGLDLS SGLVVTSLCK SSSLPASQNN LRH |
Additional Info
| Tissue Specificity | Expressed in retina pigment epithelial cells (at protein level). Widely expressed. |
| Function | Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. May play a role as an effector of ARL2. |
| Protein Name | Adp-Ribosylation Factor-Like Protein 2-Binding ProteinArf-Like 2-Binding ProteinArl2-Binding ProteinBinder Of Arf2 Protein 1 |
| Database Links | Reactome: R-HSA-83936 |
| Cellular Localisation | CytoplasmMitochondrion Intermembrane SpaceCytoskeletonMicrotubule Organizing CenterCentrosomeNucleusSpindleCilium Basal BodyThe Complex Formed With Arl2bpArl2 And Slc25a4 Is Expressed In MitochondriaDetected In The Midbody MatrixNot Detected In The GolgiNucleus And On The Mitotic SpindleCentrosome-Associated Throughout The Cell CycleNot Detected To Interphase MicrotubulesIn Retina Photoreceptor CellsLocalized In The Distal Connecting CiliaBasal BodyCiliary-Associated CentrioleAnd Ciliary RootletInteraction With Arl2 May Be Required For Cilia Basal Body Localization |
| Alternative Protein Names | Adp-Ribosylation Factor-Like Protein 2-Binding Protein proteinArf-Like 2-Binding Protein proteinArl2-Binding Protein proteinBinder Of Arf2 Protein 1 proteinARL2BP proteinBART proteinBART1 protein |
Information sourced from Uniprot.org