Human BAFF-R (CD268) protein (Recombinant) (STJP000674)

Name: Human BAFF-R (CD268) protein (Recombinant) (STJP000674)
SKU: STJP000674
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostHEK293

ConjugationUnconjugated

ImmunogenDNA sequence encoding Human BAFF-R extracellular domain was expressed in HEK293 cells NA

STJP000674

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Short Description	Recombinant-Human BAFF-R (CD268)-protein was developed from hek293. For use in research applications.
Host	HEK293
Note	STRICTLY FOR FURTHER RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Conjugation	Unconjugated
Dilution Range	Spin the vial and reconstite in distilled water to a concentration not less than 0.1 mg/mL. This can then be diluted into other buffers.
Formulation	Lyophilised from 0.2 Mu m filtered solution in 0.5% glycine, 0.5% sucrose,.01% Tween80, mM Glutamic acid, pH7.5.
Storage Instruction	Can be stored in working aliquots at°C-°C C for one month, or at-20°C C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. NA
Endotoxin	Endotoxin content was assayed using a LAL gel clot method. Endotoxin level was found to be less than.1 ng/µg (1EU/µg). NA
Immunoreactivity	The ED (50) was determined by the ability to block BAFF induced survival of splenocyte cells, and was found to be in the range of.0-5.0 ug/ml. NA

Gene Symbol	TNFRSF13C
Gene ID	115650
Uniprot ID	TR13C_HUMAN
Immunogen	DNA sequence encoding Human BAFF-R extracellular domain was expressed in HEK293 cells NA
Immunogen Region	ECD
Immunogen Sequence	MRRGPRSLRG RDAPAPTPCV PAECFDLLVR HCVACGLLRT PRPKPAGASS PAPRTALQPQ ESVGAGAGEA ALPLPGLL FG APALLGLALV LALVLVGLVS WRRRQRRLRG ASSAEAPDGD NA

Tissue Specificity	Highly expressed in spleen and lymph node, and in resting B-cells. Detected at lower levels in activated B-cells, resting CD4+ T-cells, in thymus and peripheral blood leukocytes.
Function	B-cell receptor specific for TNFSF13B/TALL1/BAFF/BLyS. Promotes the survival of mature B-cells and the B-cell response.
Protein Name	Tumor Necrosis Factor Receptor Superfamily Member 13c B-Cell-Activating Factor Receptor Baff Receptor Baff-R Blys Receptor 3 Cd Antigen Cd268
Database Links	Reactome: R-HSA-5668541 Reactome: R-HSA-5676594
Cellular Localisation	Membrane Single-Pass Type Iii Membrane Protein
Alternative Protein Names	Tumor Necrosis Factor Receptor Superfamily Member 13c protein B-Cell-Activating Factor Receptor protein Baff Receptor protein Baff-R protein Blys Receptor 3 protein Cd Antigen Cd268 protein TNFRSF13C protein BAFFR protein BR3 protein

Information sourced from Uniprot.org