Human B4GALT5 protein (Recombinant) (N-His) (STJP010664)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human B4GALT5-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | B4GALT5 |
| Gene ID | 9334 |
| Uniprot ID | B4GT5_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Glu131-Tyr388 |
Additional Info
| Function | Catalyzes the synthesis of lactosylceramide (LacCer) via the transfer of galactose from UDP-galactose to glucosylceramide (GlcCer). LacCer is the starting point in the biosynthesis of all gangliosides (membrane-bound glycosphingolipids) which play pivotal roles in the CNS including neuronal maturation and axonal and myelin formation. Plays a role in the glycosylation of BMPR1A and regulation of its protein stability. Essential for extraembryonic development during early embryogenesis. |
| Protein Name | Beta-1 -4-Galactosyltransferase 5Beta-1 -4-Galtase 5Beta4gal-T5B4gal-T5Beta-1 -4-Galt IiGlucosylceramide Beta-1 -4-GalactosyltransferaseLactosylceramide SynthaseLaccer SynthaseUdp-Gal -Beta-Glcnac Beta-1 -4-Galactosyltransferase 5Udp-Galactose -Beta-N-Acetylglucosamine Beta-1 -4-Galactosyltransferase 5 |
| Database Links | Reactome: R-HSA-2022854Reactome: R-HSA-913709Reactome: R-HSA-975577Reactome: R-HSA-9840309 |
| Cellular Localisation | Golgi ApparatusGolgi Stack MembraneSingle-Pass Type Ii Membrane ProteinTrans Cisternae Of Golgi Stack |
| Alternative Protein Names | Beta-1 -4-Galactosyltransferase 5 proteinBeta-1 -4-Galtase 5 proteinBeta4gal-T5 proteinB4gal-T5 proteinBeta-1 -4-Galt Ii proteinGlucosylceramide Beta-1 -4-Galactosyltransferase proteinLactosylceramide Synthase proteinLaccer Synthase proteinUdp-Gal -Beta-Glcnac Beta-1 -4-Galactosyltransferase 5 proteinUdp-Galactose -Beta-N-Acetylglucosamine Beta-1 -4-Galactosyltransferase 5 proteinB4GALT5 protein |
Information sourced from Uniprot.org