| Applications: | ELISA |
| Reactivity: | Human |
| Note: | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
| Sensitivity: | 0.053ng/mL |
| Detection Limit: | 0.156-10ng/mL |
| Short Description: | This b3GAT1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids.. |
| Storage Instruction: | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time: | 3 hrs |
| Gene Symbol: | B3GAT1 |
| Gene ID: | 27087 |
| Uniprot ID: | B3GA1_HUMAN |
| Immunogen Region: | Ready-To-Use |
| Sample Type: | tissue homogenates, cell lysates or other biological fluids. |
| Tissue Specificity | Mainly expressed in the brain. |
| Post Translational Modifications | The soluble form derives from the membrane form by proteolytic processing. |
| Function | Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group. |
| Protein Name | Galactosylgalactosylxylosylprotein 3-Beta-Glucuronosyltransferase 1 Beta-1 -3-Glucuronyltransferase 1 Glucuronosyltransferase P Glcat-P Udp-Glcua -Glycoprotein Beta-1 -3-Glucuronyltransferase Glcuat-P |
| Database Links | Reactome: R-HSA-1971475 |
| Cellular Localisation | Isoform 1: Golgi Apparatus Membrane Single-Pass Type Ii Membrane Protein Secreted Isoform 2: Golgi Apparatus Membrane Endoplasmic Reticulum Membrane |
| Alternative ELISA Names | Galactosylgalactosylxylosylprotein 3-Beta-Glucuronosyltransferase 1 ELISA kit Beta-1 -3-Glucuronyltransferase 1 ELISA kit Glucuronosyltransferase P ELISA kit Glcat-P ELISA kit Udp-Glcua -Glycoprotein Beta-1 -3-Glucuronyltransferase ELISA kit Glcuat-P ELISA kit B3GAT1 ELISA kit GLCATP ELISA kit |
| output |
Information sourced from Uniprot.org
