Human b3GAT1 (Beta-1, 3-Glucuronyltransferase 1) Sandwich ELISA Kit (STJE0007415)
SPECIFICATIONS
General Information
| Short Description | This b3GAT1 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.053ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 4.5 hrs |
Target Information
| Gene Symbol | B3GAT1 |
| Gene ID | 27087 |
| Uniprot ID | B3GA1_HUMAN |
| Sample Type | tissue homogenates, cell lysates or other biological fluids. |
Additional Info
| Tissue Specificity | Mainly expressed in the brain. |
| Post Translational Modifications | The soluble form derives from the membrane form by proteolytic processing. |
| Function | Involved in the biosynthesis of L2/HNK-1 carbohydrate epitope on glycoproteins. Can also play a role in glycosaminoglycan biosynthesis. Substrates include asialo-orosomucoid (ASOR), asialo-fetuin, and asialo-neural cell adhesion molecule. Requires sphingomyelin for activity: stearoyl-sphingomyelin was the most effective, followed by palmitoyl-sphingomyelin and lignoceroyl-sphingomyelin. Activity was demonstrated only for sphingomyelin with a saturated fatty acid and not for that with an unsaturated fatty acid, regardless of the length of the acyl group. |
| Protein Name | Galactosylgalactosylxylosylprotein 3-Beta-Glucuronosyltransferase 1Beta-1 -3-Glucuronyltransferase 1Glucuronosyltransferase PGlcat-PUdp-Glcua -Glycoprotein Beta-1 -3-GlucuronyltransferaseGlcuat-P |
| Database Links | Reactome: R-HSA-1971475 |
| Cellular Localisation | Isoform 1: Golgi Apparatus MembraneSingle-Pass Type Ii Membrane ProteinSecretedIsoform 2: Golgi Apparatus MembraneEndoplasmic Reticulum Membrane |
| Alternative ELISA Names | Galactosylgalactosylxylosylprotein 3-Beta-Glucuronosyltransferase 1 ELISA kitBeta-1 -3-Glucuronyltransferase 1 ELISA kitGlucuronosyltransferase P ELISA kitGlcat-P ELISA kitUdp-Glcua -Glycoprotein Beta-1 -3-Glucuronyltransferase ELISA kitGlcuat-P ELISA kitB3GAT1 ELISA kitGLCATP ELISA kit |
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Information sourced from Uniprot.org