Human ATPIF1 protein (Recombinant) (His-Tag) (STJP017739)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human ATPIF1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 50% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ATP5IF1 |
| Gene ID | 93974 |
| Uniprot ID | ATIF1_HUMAN |
| Accession Number | NP_057395.1 |
| Immunogen | Human |
| Immunogen Region | 26-106aa |
| Immunogen Sequence |
Additional Info
| Post Translational Modifications | Exhibits variability in chain length, mitochondria have distinct pools of protein cleaved after the 24th, 25th, and 26th amino acid. |
| Function | Endogenous F(1)F(o)-ATPase inhibitor limiting ATP depletion when the mitochondrial membrane potential falls below a threshold and the F(1)F(o)-ATP synthase starts hydrolyzing ATP to pump protons out of the mitochondrial matrix. Required to avoid the consumption of cellular ATP when the F(1)F(o)-ATP synthase enzyme acts as an ATP hydrolase. Indirectly acts as a regulator of heme synthesis in erythroid tissues: regulates heme synthesis by modulating the mitochondrial pH and redox potential, allowing FECH to efficiently catalyze the incorporation of iron into protoporphyrin IX to produce heme. |
| Protein Name | Atpase Inhibitor - MitochondrialAtp Synthase F1 Subunit EpsilonInhibitor Of F(1f(O-AtpaseIf(1If1 |
| Database Links | |
| Cellular Localisation | Mitochondrion |
| Alternative Protein Names | Atpase Inhibitor - Mitochondrial proteinAtp Synthase F1 Subunit Epsilon proteinInhibitor Of F(1f(O-Atpase proteinIf(1 proteinIf1 proteinATP5IF1 proteinATPI proteinATPIF1 protein |
Information sourced from Uniprot.org