Human ATP8B3 protein (Recombinant) (N-His) (STJP016351)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human ATP8B3-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 1 mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for further information. |
Target Information
| Gene Symbol | ATP8B3 |
| Gene ID | 148229 |
| Uniprot ID | AT8B3_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Asn503-Leu741 |
Additional Info
| Function | P4-ATPase flippase which catalyzes the hydrolysis of ATP coupled to the transport of aminophospholipids from the outer to the inner leaflet of various membranes and ensures the maintenance of asymmetric distribution of phospholipids. Phospholipid translocation also seems to be implicated in vesicle formation and in uptake of lipid signaling molecules. May be responsible for the maintenance of asymmetric distribution of phosphatidylserine (PS) in spermatozoa membranes. Involved in acrosome reactions and binding of spermatozoa to zona pellucida. |
| Protein Name | Phospholipid-Transporting Atpase IkAtpase Class I Type 8b Member 3 |
| Database Links | Reactome: R-HSA-936837 |
| Cellular Localisation | Cytoplasmic VesicleSecretory VesicleAcrosome MembraneMulti-Pass Membrane ProteinEndoplasmic Reticulum Membrane |
| Alternative Protein Names | Phospholipid-Transporting Atpase Ik proteinAtpase Class I Type 8b Member 3 proteinATP8B3 proteinATP1K proteinFOS37502_2 protein |
Information sourced from Uniprot.org