Human ATP5F1 protein (Recombinant) (His-Tag) (STJP018616)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human ATP5F1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Denatured |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.4M urea, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ATP5PB |
| Gene ID | 515 |
| Uniprot ID | AT5F1_HUMAN |
| Accession Number | NP_001679 |
| Immunogen | Human |
| Immunogen Region | 83-256aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGSLILYALS KEIYVISAET FTALSVLGVM VYGIKKYGPF VADFADKLNE QKLAQLEEAK QASIQHIQNA IDTEKSQQAL VQKRHYLFDV QRNNIAMALE VTYRERLYRV YKEVKNRLDY HISVQNMMRR KEQEHMINWV EKHVVQSIST QQEKETIAKC IADLKLLAKK AQAQPVM |
Additional Info
| Function | Subunit b, of the mitochondrial membrane ATP synthase complex (F(1)F(0) ATP synthase or Complex V) that produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. ATP synthase complex consist of a soluble F(1) head domain - the catalytic core - and a membrane F(1) domain - the membrane proton channel. These two domains are linked by a central stalk rotating inside the F(1) region and a stationary peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation (Probable). In vivo, can only synthesize ATP although its ATP hydrolase activity can be activated artificially in vitro. Part of the complex F(0) domain. Part of the complex F(0) domain and the peripheric stalk, which acts as a stator to hold the catalytic alpha(3)beta(3) subcomplex and subunit a/ATP6 static relative to the rotary elements. |
| Protein Name | Atp Synthase Peripheral Stalk Subunit B - MitochondrialAtp Synthase F(0 Complex Subunit B1 - MitochondrialAtp Synthase Peripheral Stalk-Membrane Subunit BAtp Synthase Proton-Transporting Mitochondrial F(0 Complex Subunit B1Atp Synthase Subunit BAtpase Subunit B |
| Database Links | Reactome: R-HSA-163210Reactome: R-HSA-8949613 |
| Cellular Localisation | MitochondrionMitochondrion Inner Membrane |
| Alternative Protein Names | Atp Synthase Peripheral Stalk Subunit B - Mitochondrial proteinAtp Synthase F(0 Complex Subunit B1 - Mitochondrial proteinAtp Synthase Peripheral Stalk-Membrane Subunit B proteinAtp Synthase Proton-Transporting Mitochondrial F(0 Complex Subunit B1 proteinAtp Synthase Subunit B proteinAtpase Subunit B proteinATP5PB proteinATP5F1 protein |
Information sourced from Uniprot.org