Human ATP2A1 protein (Recombinant) (N-His) (STJP008058)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human ATP2A1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | ATP2A1 |
| Gene ID | 487 |
| Uniprot ID | AT2A1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Thr357-Leu600 |
Additional Info
| Function | Key regulator of striated muscle performance by acting as the major Ca(2+) ATPase responsible for the reuptake of cytosolic Ca(2+) into the sarcoplasmic reticulum. Catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol to the sarcoplasmic reticulum lumen. Contributes to calcium sequestration involved in muscular excitation/contraction. |
| Protein Name | Sarcoplasmic/Endoplasmic Reticulum Calcium Atpase 1Serca1Sr Ca(2+-Atpase 1Calcium Pump 1Calcium-Transporting Atpase Sarcoplasmic Reticulum Type - Fast Twitch Skeletal Muscle IsoformEndoplasmic Reticulum Class 1/2 Ca(2+ Atpase |
| Database Links | Reactome: R-HSA-1912420Reactome: R-HSA-418359Reactome: R-HSA-5578775Reactome: R-HSA-936837 |
| Cellular Localisation | Endoplasmic Reticulum MembraneMulti-Pass Membrane ProteinSarcoplasmic Reticulum Membrane |
| Alternative Protein Names | Sarcoplasmic/Endoplasmic Reticulum Calcium Atpase 1 proteinSerca1 proteinSr Ca(2+-Atpase 1 proteinCalcium Pump 1 proteinCalcium-Transporting Atpase Sarcoplasmic Reticulum Type - Fast Twitch Skeletal Muscle Isoform proteinEndoplasmic Reticulum Class 1/2 Ca(2+ Atpase proteinATP2A1 protein |
Information sourced from Uniprot.org