Human ATF1 protein (Recombinant) (C-His) (STJP014437)
SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human ATF1-C-His protein was developed from e.coli and has a target region of C-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a 0.22 Mu m filtered solution in PBS, pH 7.4. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/µg as determined by LAL test. |
Target Information
| Gene Symbol | ATF1 |
| Gene ID | 466 |
| Uniprot ID | ATF1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Val271 |
Additional Info
| Function | This protein binds the cAMP response element (CRE) (consensus: 5'-GTGACGTACAG-3'), a sequence present in many viral and cellular promoters. Binds to the Tax-responsive element (TRE) of HTLV-I. Mediates PKA-induced stimulation of CRE-reporter genes. Represses the expression of FTH1 and other antioxidant detoxification genes. Triggers cell proliferation and transformation. |
| Protein Name | Cyclic Amp-Dependent Transcription Factor Atf-1Camp-Dependent Transcription Factor Atf-1Activating Transcription Factor 1Protein Treb36 |
| Database Links | Reactome: R-HSA-199920Reactome: R-HSA-9031628 |
| Cellular Localisation | Nucleus |
| Alternative Protein Names | Cyclic Amp-Dependent Transcription Factor Atf-1 proteinCamp-Dependent Transcription Factor Atf-1 proteinActivating Transcription Factor 1 proteinProtein Treb36 proteinATF1 protein |
Information sourced from Uniprot.org