Human ASS1 protein (Recombinant) (N-His) (STJP014319)
SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human ASS1-N-His protein was developed from e.coli and has a target region of N-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Formulation | Supplied as a 0.22 Mu m filtered solution in 20mM PB, 150mM NaCl, 50mM Imidazole, 1mM DTT, 40% Glycerol, pH 7.5. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8ยฐC for one week. Store at-20 to-80ยฐC for twelve months from the date of receipt. |
| Endotoxin | < 1 EU/ยตg as determined by LAL test. |
Target Information
| Gene Symbol | ASS1 |
| Gene ID | 445 |
| Uniprot ID | ASSY_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Lys412 |
Additional Info
| Post Translational Modifications | Acetylated by CLOCK in a circadian manner which negatively regulates its enzyme activity. Deacetylated by histone deacetylases. |
| Function | One of the enzymes of the urea cycle, the metabolic pathway transforming neurotoxic amonia produced by protein catabolism into inocuous urea in the liver of ureotelic animals. Catalyzes the formation of arginosuccinate from aspartate, citrulline and ATP and together with ASL it is responsible for the biosynthesis of arginine in most body tissues. |
| Protein Name | Argininosuccinate SynthaseCitrulline--Aspartate Ligase |
| Database Links | Reactome: R-HSA-70635 |
| Cellular Localisation | CytoplasmCytosol |
| Alternative Protein Names | Argininosuccinate Synthase proteinCitrulline--Aspartate Ligase proteinASS1 proteinASS protein |
Information sourced from Uniprot.org