Human ASRGL1 protein (Recombinant) (N-His) (STJP007616)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human ASRGL1-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | ASRGL1 |
| Gene ID | 80150 |
| Uniprot ID | ASGL1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Met1-Pro308 |
Additional Info
| Post Translational Modifications | Cleaved into an alpha and beta chain by autocatalysis.this activates the enzyme. The N-terminal residue of the beta subunit is responsible for the nucleophile hydrolase activity. |
| Function | Has both L-asparaginase and beta-aspartyl peptidase activity. May be involved in the production of L-aspartate, which can act as an excitatory neurotransmitter in some brain regions. Is highly active with L-Asp beta-methyl ester. Besides, has catalytic activity toward beta-aspartyl dipeptides and their methyl esters, including beta-L-Asp-L-Phe, beta-L-Asp-L-Phe methyl ester (aspartame), beta-L-Asp-L-Ala, beta-L-Asp-L-Leu and beta-L-Asp-L-Lys. Does not have aspartylglucosaminidase activity and is inactive toward GlcNAc-L-Asn. Likewise, has no activity toward glutamine. |
| Protein Name | Isoaspartyl Peptidase/L-AsparaginaseAsparaginase-Like Protein 1Beta-Aspartyl-PeptidaseIsoaspartyl DipeptidaseL-Asparagine Amidohydrolase Cleaved Into - Isoaspartyl Peptidase/L-Asparaginase Alpha Chain - Isoaspartyl Peptidase/L-Asparaginase Beta Chain |
| Database Links | Reactome: R-HSA-8964208 |
| Cellular Localisation | CytoplasmMidpiece Of Sperm Tail |
| Alternative Protein Names | Isoaspartyl Peptidase/L-Asparaginase proteinAsparaginase-Like Protein 1 proteinBeta-Aspartyl-Peptidase proteinIsoaspartyl Dipeptidase proteinL-Asparagine Amidohydrolase Cleaved Into - Isoaspartyl Peptidase/L-Asparaginase Alpha Chain - Isoaspartyl Peptidase/L-Asparaginase Beta Chain proteinASRGL1 proteinALP proteinCRASH protein |
Information sourced from Uniprot.org