Human ASMT protein (Recombinant) (His-Tag) (STJP017897)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human ASMT-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE/Denatured |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 1M urea, 10% Glycerol |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ASMT |
| Gene ID | 438 |
| Uniprot ID | ASMT_HUMAN |
| Accession Number | AAH01620 |
| Immunogen | Human |
| Immunogen Region | 1-298aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Expressed in the pineal gland (at protein level). In the retina, very low expression is found at the mRNA level, and not at the protein level. |
| Function | Isoform 1: Catalyzes the transfer of a methyl group onto N-acetylserotonin, producing melatonin (N-acetyl-5-methoxytryptamine). Isoform 2: Does not show Acetylserotonin O-methyltransferase activity. Isoform 3: Does not show Acetylserotonin O-methyltransferase activity. |
| Protein Name | Acetylserotonin O-MethyltransferaseHydroxyindole O-MethyltransferaseHiomt |
| Database Links | Reactome: R-HSA-209931 |
| Cellular Localisation | |
| Alternative Protein Names | Acetylserotonin O-Methyltransferase proteinHydroxyindole O-Methyltransferase proteinHiomt proteinASMT protein |
Information sourced from Uniprot.org