Human ASGR2 protein (Recombinant) (His-Tag) (STJP017884)

Name: Human ASGR2 protein (Recombinant) (His-Tag) (STJP017884)
SKU: STJP017884
Availability: InStock

⇓ Datasheet ⇓ SDS

SPECIFICATIONS

HostE.coli

ImmunogenHuman

STJP017884

Current Stock:

🚚 Free UK Delivery on orders over £150

Quantity:

Processing The item has been added

Enquire For Bulk Order

✓ 1-Year Performance Guarantee | SDS & Datasheet Included | Expert Tech Support | Covered by St John's Laboratory Guarantee

Short Description	Recombinant-Human ASGR2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
Applications	SDS-PAGE
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	0.5 mg/mL
Formulation	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 30% Glycerol, 1mM DTT
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol	ASGR2
Gene ID	433
Uniprot ID	ASGR2_HUMAN
Accession Number	NP_001172
Immunogen	Human
Immunogen Region	80-311aa
Immunogen Sequence	MGSSHHHHHH SSGLVPRGSH MGSQSEGHRG AQLQAELRSL KEAFSNFSSS TLTEVQAIST HGGSVGDKIT SLGAKLEKQQ QDLKADHDAL LFHLKHFPVD LRFVACQMEL LHSNGSQRTC CPVNWVEHQG SCYWFSHSGK AWAEAEKYCQ LENAHLVVIN SWEEQKFIVQ HTNPFNTWIG LTDSDGSWKW VDGTDYRHNY KNWAVTQPDN WHGHELGGSE DCVEVQPD

Tissue Specificity	Expressed exclusively in hepatic parenchymal cells.
Function	Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface.
Protein Name	Asialoglycoprotein Receptor 2 Asgp-R 2 Asgpr 2 C-Type Lectin Domain Family 4 Member H2 Hepatic Lectin H2 Hl-2
Database Links	Reactome: R-HSA-446203
Cellular Localisation	Membrane Single-Pass Type Ii Membrane Protein
Alternative Protein Names	Asialoglycoprotein Receptor 2 protein Asgp-R 2 protein Asgpr 2 protein C-Type Lectin Domain Family 4 Member H2 protein Hepatic Lectin H2 protein Hl-2 protein ASGR2 protein CLEC4H2 protein

Information sourced from Uniprot.org