Human ASC1 (Asc Type Amino Acid Transporter 1) Sandwich ELISA Kit Ready-To-Use Kit (STJE0013707)
SPECIFICATIONS
General Information
| Short Description | This ASC1 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates, cell lysates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.063ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | SLC7A10 |
| Gene ID | 56301 |
| Uniprot ID | AAA1_HUMAN |
| Immunogen Region | Ready-To-Use |
| Sample Type | tissue homogenates, cell lysates or other biological fluids. |
Additional Info
| Tissue Specificity | Expressed in brain, heart, kidney, liver, lung, pancreas, placenta, and skeletal muscle. |
| Post Translational Modifications | |
| Function | Associates with SLC3A2/4F2hc to form a functional heterodimeric complex that translocates small neutral L- and D-amino acids across the plasma membrane. Preferentially mediates exchange transport, but can also operate via facilitated diffusion. Acts as a major transporter for glycine, L- and D-serine in the central nervous system. At the spinal cord and brainstem regulates glycine metabolism and glycinergic inhibitory neurotransmission by providing for glycine de novo synthesis from L-serine and glycine recycling from astrocytes to glycinergic motor neurons. At Schaffer collateral-CA1 synapses mediates D-serine and glycine release that modulates post-synaptic activation of NMDA receptors and excitatory glutamatergic transmission. May regulate D-serine release from mesenchymal progenitors located in developing subcutaneous adipose tissue, favoring white adipocyte over thermogenic beige adipocyte lineage commitment. |
| Protein Name | Asc-Type Amino Acid Transporter 1Asc-1Solute Carrier Family 7 Member 10 |
| Database Links | Reactome: R-HSA-210991Reactome: R-HSA-352230 |
| Cellular Localisation | Cell MembraneMulti-Pass Membrane ProteinColocalizes With Olig2 In Astrocytic ProcessesLocalizes To The Plasma Membrane In Mature Adipocytes And To Intracellular Structures In Preadipocytes |
| Alternative ELISA Names | Asc-Type Amino Acid Transporter 1 ELISA kitAsc-1 ELISA kitSolute Carrier Family 7 Member 10 ELISA kitSLC7A10 ELISA kitASC1 ELISA kit |
| output |
Information sourced from Uniprot.org