Human ASB9 protein (Recombinant) (N-His) (STJP008174)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human ASB9-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | ASB9 |
| Gene ID | 140462 |
| Uniprot ID | ASB9_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Ser38-Leu294 |
Additional Info
| Function | Substrate-recognition component of a cullin-5-RING E3 ubiquitin-protein ligase complex (ECS complex, also named CRL5 complex), which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. The ECS(ASB9) complex catalyzes ubiquitination of creatine kinases CKB and CKMT1A. Isoform 2: Does not interact with the Elongin BC complex, likely to be a negative regulator of isoform 1. |
| Protein Name | Ankyrin Repeat And Socs Box Protein 9Asb-9 |
| Database Links | Reactome: R-HSA-8951664Reactome: R-HSA-983168 |
| Cellular Localisation | Mitochondrion |
| Alternative Protein Names | Ankyrin Repeat And Socs Box Protein 9 proteinAsb-9 proteinASB9 protein |
Information sourced from Uniprot.org