Human ARPC4 (Actin Related Protein 2/3 Complex Subunit 4) Sandwich ELISA Kit (STJE0007320)

Human ARPC4 (Actin Related Protein 2/3 Complex Subunit 4) Sandwich ELISA Kit (STJE0007320)

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STJE0007320
$581.67 - $809.37
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Short Description :This ARPC4 Sandwich ELISA Kit is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids..
Applications:ELISA
Reactivity:Human
Sensitivity:0.115ng/mL
Detection Limit:0.312-20ng/mL
Note:STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.
Storage Instruction:Store the unopened kit in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit.
Assay Time:4.5 hrs
Gene Symbol:ARPC4
Gene ID:10093
Uniprot ID:ARPC4_HUMAN
Sample Type:tissue homogenates or other biological fluids.
Tissue Specificity
Post Translational Modifications
Function Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs).
Protein Name Actin-Related Protein 2/3 Complex Subunit 4
Arp2/3 Complex 20 Kda Subunit
P20-Arc
Database Links Reactome: R-HSA-2029482
Reactome: R-HSA-3928662
Reactome: R-HSA-5663213
Reactome: R-HSA-8856828
Reactome: R-HSA-9664422
Cellular Localisation Cytoplasm
Cytoskeleton
Cell Projection
Nucleus
Alternative ELISA Names Actin-Related Protein 2/3 Complex Subunit 4 ELISA kit
Arp2/3 Complex 20 Kda Subunit ELISA kit
P20-Arc ELISA kit
ARPC4 ELISA kit
ARC20 ELISA kit
output

Information sourced from Uniprot.org

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