Human ARPC2 (Actin Related Protein 2/3 Complex Subunit 2) Sandwich ELISA Kit Ready-To-Use Kit (STJE0013695)
SPECIFICATIONS
General Information
| Short Description | This ARPC2 Sandwich ELISA Kit, Ready-To-Use is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human tissue homogenates or other biological fluids.. |
| Applications | ELISA |
| Reactivity | Human |
| Sensitivity | 0.068ng/mL |
| Detection Limit | 0.156-10ng/mL |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Storage Instruction | The whole kit may be stored at-20°C for up to 12 months from receipt. An unopened kit may be stored in the fridge at 2-8°C for up to 6 months. Once opened store individual kit contents according to components table provided with the kit. |
| Assay Time | 3 hrs |
Target Information
| Gene Symbol | ARPC2 |
| Gene ID | 10109 |
| Uniprot ID | ARPC2_HUMAN |
| Immunogen Region | Ready-To-Use |
| Sample Type | tissue homogenates or other biological fluids. |
Additional Info
| Tissue Specificity | |
| Post Translational Modifications | |
| Function | Actin-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the mother actin filament. In addition to its role in the cytoplasmic cytoskeleton, the Arp2/3 complex also promotes actin polymerization in the nucleus, thereby regulating gene transcription and repair of damaged DNA. The Arp2/3 complex promotes homologous recombination (HR) repair in response to DNA damage by promoting nuclear actin polymerization, leading to drive motility of double-strand breaks (DSBs). |
| Protein Name | Actin-Related Protein 2/3 Complex Subunit 2Arp2/3 Complex 34 Kda SubunitP34-Arc |
| Database Links | Reactome: R-HSA-2029482Reactome: R-HSA-3928662Reactome: R-HSA-5663213Reactome: R-HSA-8856828Reactome: R-HSA-9664422 |
| Cellular Localisation | CytoplasmCytoskeletonCell ProjectionSynapseSynaptosomeNucleus |
| Alternative ELISA Names | Actin-Related Protein 2/3 Complex Subunit 2 ELISA kitArp2/3 Complex 34 Kda Subunit ELISA kitP34-Arc ELISA kitARPC2 ELISA kitARC34 ELISA kitPRO2446 ELISA kit |
| output |
Information sourced from Uniprot.org