Human ARFL1/ARL1 protein (Recombinant) (His-Tag) (STJP016800)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human ARFL1/ARL1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.25 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 40% Glycerol, 100mM NaCl, 2mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | ARL1 |
| Gene ID | 400 |
| Uniprot ID | ARL1_HUMAN |
| Accession Number | NP_001168 |
| Immunogen | Human |
| Immunogen Region | 1-181aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MGGFFSSIFS SLFGTREMRI LILGLDGAGK TTILYRLQVG EVVTTIPTIG FNVETVTYKN LKFQVWDLGG QTSIRPYWRC YYSNTDAVIY VVDSCDRDRI GISKSELVAM LEEEELRKAI LVVFANKQDM EQAMTSSEMA NSLGLPALKD RKWQIFKTSA TKGTGLDEAM EWLVETLKSR Q |
Additional Info
| Tissue Specificity | Detected in heart, liver, lung and liver (at protein level). Detected in fetal heart, lung, liver and kidney. Detected in adult heart, placenta, lung, liver, skeletal muscle, kidney and pancreas. |
| Function | GTP-binding protein that recruits several effectors, such as golgins, arfaptins and Arf-GEFs to the trans-Golgi network, and modulates their functions at the Golgi complex. Plays thereby a role in a wide range of fundamental cellular processes, including cell polarity, innate immunity, or protein secretion mediated by arfaptins, which were shown to play a role in maintaining insulin secretion from pancreatic beta cells. |
| Protein Name | Adp-Ribosylation Factor-Like Protein 1 |
| Database Links | Reactome: R-HSA-6811440 |
| Cellular Localisation | Golgi Apparatus MembranePeripheral Membrane ProteinCytoplasmic SideGolgi ApparatusTrans-Golgi Network MembraneMembraneLipid-Anchor |
| Alternative Protein Names | Adp-Ribosylation Factor-Like Protein 1 proteinARL1 protein |
Information sourced from Uniprot.org