Human APRIL/TNFSF13 protein (Recombinant) (T7-Tag) (STJP018701)

Name: Human APRIL/TNFSF13 protein (Recombinant) (T7-Tag) (STJP018701)
SKU: STJP018701
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⇓ Datasheet ⇓ SDS Citations

SPECIFICATIONS

HostE.coli

ImmunogenHuman

STJP018701

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Short Description	Recombinant-Human APRIL/TNFSF13-T7-Tag protein was developed from e.coli and has a target region of T7-Tag. For use in research applications.
Applications	SDS-PAGE/Denatured
Host	E.coli
Note	STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Concentration	1 mg/mL
Formulation	Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 10% Glycerol, 0.4M Urea
Storage Instruction	For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Gene Symbol	TNFSF13
Gene ID	8741
Uniprot ID	TNF13_HUMAN
Accession Number	NP_742085
Immunogen	Human
Immunogen Region	105-247aa
Immunogen Sequence	AVLT QKQKKQHSVL HLVPINATSK DDSDVTEVMW QPALRRGRGL QAQGYGVRIQ DAGVYLLYSQ VLFQDVTFTM GQVVSREGQG RQETLFRCIR SMPSHPDRAY NSCYSAGVFH LHQGDILSVI IPRARAKLNL SPHGTFLGL

Tissue Specificity	Expressed at high levels in transformed cell lines, cancers of colon, thyroid, lymphoid tissues and specifically expressed in monocytes and macrophages.
Post Translational Modifications	The precursor is cleaved by furin.
Function	Cytokine that binds to TNFRSF13B/TACI and to TNFRSF17/BCMA. Plays a role in the regulation of tumor cell growth. May be involved in monocyte/macrophage-mediated immunological processes.
Protein Name	Tumor Necrosis Factor Ligand Superfamily Member 13 A Proliferation-Inducing Ligand April Tnf- And Apol-Related Leukocyte Expressed Ligand 2 Tall-2 Tnf-Related Death Ligand 1 Trdl-1 Cd Antigen Cd256
Database Links	Reactome: R-HSA-450520 Reactome: R-HSA-5669034
Cellular Localisation	Secreted
Alternative Protein Names	Tumor Necrosis Factor Ligand Superfamily Member 13 protein A Proliferation-Inducing Ligand protein April protein Tnf- And Apol-Related Leukocyte Expressed Ligand 2 protein Tall-2 protein Tnf-Related Death Ligand 1 protein Trdl-1 protein Cd Antigen Cd256 protein TNFSF13 protein APRIL protein TALL2 protein ZTNF2 protein UNQ383 protein PRO715 protein

Information sourced from Uniprot.org