Human Apolipoprotein H/APOH protein (Recombinant) (His-Tag) (STJP017939)

SPECIFICATIONS
HostE.coli
ImmunogenHuman
STJP017939
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General Information

Short DescriptionRecombinant-Human Apolipoprotein H/APOH-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications.
ApplicationsSDS-PAGE/Denatured
HostE.coli
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Concentration0.5 mg/mL
FormulationLiquid in 20mM Tris-HCl buffer (pH 8.0) containing 2M urea, 10% Glycerol
Storage InstructionFor short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles.

Target Information

Gene SymbolAPOH
Gene ID350
Uniprot IDAPOH_HUMAN
Accession NumberNP_000033
ImmunogenHuman
Immunogen Region20-345aa
Immunogen SequenceMGSSHHHHHH SSGLVPRGSH MGSGRTCPKP DDLPFSTVVP LKTFYEPGEE ITYSCKPGYV SRGGMRKFIC PLTGLWPINT LKCTPRVCPF AGILENGAVR YTTFEYPNTI SFSCNTGFYL NGADSAKCTE EGKWSPELPV CAPIICPPPS IPTFATLRVY KPSAGNNSLY RDTAVFECLP QHAMFGNDTI TCTTHGNWTK LPECREVKCP FPSRPDNGFV NYPAKPTL

Additional Info

Tissue Specificity Expressed by the liver and secreted in plasma.
Post Translational Modifications N- and O-glycosylated. PubMed:6587378 also reports glycosylation on 'Asn-188' for their allele.
Function Binds to various kinds of negatively charged substances such as heparin, phospholipids, and dextran sulfate. May prevent activation of the intrinsic blood coagulation cascade by binding to phospholipids on the surface of damaged cells.
Protein Name Beta-2-Glycoprotein 1
Apc Inhibitor
Activated Protein C-Binding Protein
Anticardiolipin Cofactor
Apolipoprotein H
Apo-H
Beta-2-Glycoprotein I
B2gpi
Beta(2gpi
Database Links Reactome: R-HSA-114608
Cellular Localisation Secreted
Alternative Protein Names Beta-2-Glycoprotein 1 protein
Apc Inhibitor protein
Activated Protein C-Binding Protein protein
Anticardiolipin Cofactor protein
Apolipoprotein H protein
Apo-H protein
Beta-2-Glycoprotein I protein
B2gpi protein
Beta(2gpi protein
APOH protein
B2G1 protein

Information sourced from Uniprot.org

Citations

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