Human APOC2 protein (Recombinant) (C-His) (STJP008583)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human APOC2-C-His protein was developed from e.coli for the region C-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | APOC2 |
| Gene ID | 344 |
| Uniprot ID | APOC2_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Gly22-Glu101 |
Additional Info
| Post Translational Modifications | Proapolipoprotein C-II is synthesized as a sialic acid containing glycoprotein which is subsequently desialylated prior to its proteolytic processing. Proapolipoprotein C-II, the major form found in plasma undergoes proteolytic cleavage of its N-terminal hexapeptide to generate apolipoprotein C-II, which occurs as the minor form in plasma. |
| Function | Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase. Both proapolipoprotein C-II and apolipoprotein C-II can activate lipoprotein lipase. In normolipidemic individuals, it is mainly distributed in the HDL, whereas in hypertriglyceridemic individuals, predominantly found in the VLDL and LDL. |
| Protein Name | Apolipoprotein C-IiApo-CiiApoc-IiApolipoprotein C2 Cleaved Into - Proapolipoprotein C-IiProapoc-Ii |
| Database Links | Reactome: R-HSA-8963888Reactome: R-HSA-8963889Reactome: R-HSA-8963901Reactome: R-HSA-8964058Reactome: R-HSA-9029569Reactome: R-HSA-975634 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Apolipoprotein C-Ii proteinApo-Cii proteinApoc-Ii proteinApolipoprotein C2 Cleaved Into - Proapolipoprotein C-Ii proteinProapoc-Ii proteinAPOC2 proteinAPC2 protein |
Information sourced from Uniprot.org