Human APOA1 protein (Recombinant-Active) (C-His) (STJP011781)
SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Active-Human APOA1-C-His protein was developed from e.coli and has a target region of C-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 5% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | <0.1 EU/Mu g of the protein by the LAL method. |
| Immunoreactivity | When recombinant human ApoA1 is Immobilised at 5 µg/mL (100 µL/well) , the concentration of recombinant human SR‑AI/MSR that produces 50% of the optimal binding response is approximately 0.5‑2.5 µg/mL. |
Target Information
| Gene Symbol | APOA1 |
| Gene ID | 335 |
| Uniprot ID | APOA1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Asp25-Gln267 |
Additional Info
| Post Translational Modifications | Glycosylated. Palmitoylated. Phosphorylation sites are present in the extracellular medium. |
| Function | Participates in the reverse transport of cholesterol from tissues to the liver for excretion by promoting cholesterol efflux from tissues and by acting as a cofactor for the lecithin cholesterol acyltransferase (LCAT). As part of the SPAP complex, activates spermatozoa motility. |
| Protein Name | Apolipoprotein A-IApo-AiApoa-IApolipoprotein A1 Cleaved Into - Proapolipoprotein A-IProapoa-I - Truncated Apolipoprotein A-IApolipoprotein A-I(1-242 |
| Database Links | Reactome: R-HSA-114608Reactome: R-HSA-1369062Reactome: R-HSA-1989781Reactome: R-HSA-2168880Reactome: R-HSA-3000471Reactome: R-HSA-3000480Reactome: R-HSA-381426Reactome: R-HSA-5682113Reactome: R-HSA-8957275Reactome: R-HSA-8963888Reactome: R-HSA-8963896Reactome: R-HSA-8963901Reactome: R-HSA-8964011Reactome: R-HSA-8964058Reactome: R-HSA-9707616Reactome: R-HSA-975634Reactome: R-HSA-977225 |
| Cellular Localisation | Secreted |
| Alternative Protein Names | Apolipoprotein A-I proteinApo-Ai proteinApoa-I proteinApolipoprotein A1 Cleaved Into - Proapolipoprotein A-I proteinProapoa-I - Truncated Apolipoprotein A-I proteinApolipoprotein A-I(1-242 proteinAPOA1 protein |
Information sourced from Uniprot.org