Human API5 protein (Recombinant) (N-His) (STJP005964)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human API5-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | API5 |
| Gene ID | 8539 |
| Uniprot ID | API5_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Pro2-Phe360 |
Additional Info
| Post Translational Modifications | Acetylation at Lys-251 impairs antiapoptotic function. |
| Function | Antiapoptotic factor that may have a role in protein assembly. Negatively regulates ACIN1. By binding to ACIN1, it suppresses ACIN1 cleavage from CASP3 and ACIN1-mediated DNA fragmentation. Also known to efficiently suppress E2F1-induced apoptosis. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. |
| Protein Name | Apoptosis Inhibitor 5Api-5Antiapoptosis Clone 11 ProteinAac-11Cell Migration-Inducing Gene 8 ProteinFibroblast Growth Factor 2-Interacting FactorFifProtein Xagl |
| Database Links | |
| Cellular Localisation | NucleusCytoplasmMainly NuclearCan Also Be CytoplasmicIsoform 3: Cytoplasm |
| Alternative Protein Names | Apoptosis Inhibitor 5 proteinApi-5 proteinAntiapoptosis Clone 11 Protein proteinAac-11 proteinCell Migration-Inducing Gene 8 Protein proteinFibroblast Growth Factor 2-Interacting Factor proteinFif proteinProtein Xagl proteinAPI5 proteinMIG8 protein |
Information sourced from Uniprot.org