Human APBA1 protein (Recombinant) (N-His) (STJP014600)
SPECIFICATIONS
HostE.coli
ConjugationUnconjugated
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human APBA1-N-His protein was developed from e.coli and has a target region of N-His. For use in research applications. |
| Applications | ELISA/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Conjugation | Unconjugated |
| Dilution Range | Reconstitute in sterile water for a stock solution. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 5% Trehalose, 2% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for one week. Store at-20 to-80°C for twelve months from the date of receipt. |
| Endotoxin | Please contact us for this information. |
Target Information
| Gene Symbol | APBA1 |
| Gene ID | 320 |
| Uniprot ID | APBA1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Glu453-Pro623 |
Additional Info
| Function | Putative function in synaptic vesicle exocytosis by binding to Munc18-1, an essential component of the synaptic vesicle exocytotic machinery. May modulate processing of the amyloid-beta precursor protein (APP) and hence formation of APP-beta. Component of the LIN-10-LIN-2-LIN-7 complex, which associates with the motor protein KIF17 to transport vesicles containing N-methyl-D-aspartate (NMDA) receptor subunit NR2B along microtubules. |
| Protein Name | Amyloid-Beta A4 Precursor Protein-Binding Family A Member 1Adapter Protein X11alphaNeuron-Specific X11 ProteinNeuronal Munc18-1-Interacting Protein 1Mint-1 |
| Database Links | Reactome: R-HSA-212676Reactome: R-HSA-6794361Reactome: R-HSA-9609736 |
| Cellular Localisation | CytoplasmPerinuclear RegionNucleusOnly About 5% Of The Protein Is Located In The NucleusIsoform 2: Golgi Apparatus |
| Alternative Protein Names | Amyloid-Beta A4 Precursor Protein-Binding Family A Member 1 proteinAdapter Protein X11alpha proteinNeuron-Specific X11 Protein proteinNeuronal Munc18-1-Interacting Protein 1 proteinMint-1 proteinAPBA1 proteinMINT1 proteinX11 protein |
Information sourced from Uniprot.org