Human AP3S1 protein (Recombinant) (His-Tag) (STJP017911)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human AP3S1-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 1 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% Glycerol, 1mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AP3S1 |
| Gene ID | 1176 |
| Uniprot ID | AP3S1_HUMAN |
| Accession Number | NP_001275 |
| Immunogen | Human |
| Immunogen Region | 1-193aa |
| Immunogen Sequence | MGSSHHHHHH SSGLVPRGSH MIKAILIFNN HGKPRLSKFY QPYSEDTQQQ IIRETFHLVS KRDENVCNFL EGGLLIGGSD NKLIYRHYAT LYFVFCVDSS ESELGILDLI QVFVETLDKC FENVCELDLI FHVDKVHNIL AEMVMGGMVL ETNMNEIVTQ IDAQNKLEKS EAGLAGAPAR AVSAVKNMNL PEIPRNINIG DISIKVPNLP SFK |
Additional Info
| Tissue Specificity | Present in all adult tissues examined. |
| Function | Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. |
| Protein Name | Ap-3 Complex Subunit Sigma-1Ap-3 Complex Subunit Sigma-3aAdaptor-Related Protein Complex 3 Subunit Sigma-1Clathrin-Associated/Assembly/Adaptor Protein - Small 3Sigma-3a-AdaptinSigma3a-AdaptinSigma-Adaptin 3a |
| Database Links | Reactome: R-HSA-432722 |
| Cellular Localisation | Golgi ApparatusCytoplasmic Vesicle MembranePeripheral Membrane ProteinCytoplasmic SideComponent Of The Coat Surrounding The Cytoplasmic Face Of Coated Vesicles Located At The Golgi Complex |
| Alternative Protein Names | Ap-3 Complex Subunit Sigma-1 proteinAp-3 Complex Subunit Sigma-3a proteinAdaptor-Related Protein Complex 3 Subunit Sigma-1 proteinClathrin-Associated/Assembly/Adaptor Protein - Small 3 proteinSigma-3a-Adaptin proteinSigma3a-Adaptin proteinSigma-Adaptin 3a proteinAP3S1 proteinCLAPS3 protein |
Information sourced from Uniprot.org