Human AP1S2 protein (Recombinant) (His-Tag) (STJP017221)
SPECIFICATIONS
HostE.coli
ImmunogenHuman
General Information
| Short Description | Recombinant-Human AP1S2-His-Tag protein was developed from e.coli and has a target region of His-Tag. For use in research applications. |
| Applications | SDS-PAGE |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT TO BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Concentration | 0.5 mg/mL |
| Formulation | Liquid in 20mM Tris-HCl buffer (pH 8.0) containing 40% Glycerol, 0.1M NaCl, 2mM DTT |
| Storage Instruction | For short term storage, keep at +2C to +8C for up to 1 week. For long term storage, aliquot and store at-20C, and avoid repeat freeze-thaw cycles. |
Target Information
| Gene Symbol | AP1S2 |
| Gene ID | 8905 |
| Uniprot ID | AP1S2_HUMAN |
| Accession Number | NP_003907 |
| Immunogen | Human |
| Immunogen Region | 1-157aa |
| Immunogen Sequence |
Additional Info
| Tissue Specificity | Widely expressed. |
| Function | Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the late-Golgi/trans-Golgi network (TGN) and/or endosomes. The AP complexes mediate both the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. |
| Protein Name | Ap-1 Complex Subunit Sigma-2Adaptor Protein Complex Ap-1 Subunit Sigma-1bAdaptor-Related Protein Complex 1 Subunit Sigma-1bClathrin Assembly Protein Complex 1 Sigma-1b Small ChainGolgi Adaptor Ha1/Ap1 Adaptin Sigma-1b SubunitSigma 1b Subunit Of Ap-1 ClathrinSigma-Adaptin 1bSigma1b-Adaptin |
| Database Links | Reactome: R-HSA-164940Reactome: R-HSA-2132295Reactome: R-HSA-432720Reactome: R-HSA-432722 |
| Cellular Localisation | Golgi ApparatusCytoplasmic Vesicle MembranePeripheral Membrane ProteinCytoplasmic SideMembraneClathrin-Coated PitComponent Of The Coat Surrounding The Cytoplasmic Face Of Coated Vesicles Located At The Golgi Complex |
| Alternative Protein Names | Ap-1 Complex Subunit Sigma-2 proteinAdaptor Protein Complex Ap-1 Subunit Sigma-1b proteinAdaptor-Related Protein Complex 1 Subunit Sigma-1b proteinClathrin Assembly Protein Complex 1 Sigma-1b Small Chain proteinGolgi Adaptor Ha1/Ap1 Adaptin Sigma-1b Subunit proteinSigma 1b Subunit Of Ap-1 Clathrin proteinSigma-Adaptin 1b proteinSigma1b-Adaptin proteinAP1S2 proteinDC22 protein |
Information sourced from Uniprot.org