Human AOC3/VAP-1 protein (Recombinant) (C-His) (STJP007105)

SPECIFICATIONS
HostInsect Cells
ImmunogenHomo sapiens (Human)
STJP007105
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General Information

Short DescriptionRecombinant-Human AOC3/VAP-1-C-His protein was developed from insect cells for the region C-His. For use in research applications.
ApplicationsELISA/Immunogen/SDS-PAGE/WB
HostInsect Cells
NoteSTRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS.

Product Properties

Dilution RangeReconstitute in sterile water for a stock solution.A copy of datasheet will be provided with the products, please refer to it for details.
FormulationLyophilized from a solution in PBS pH 7.4, 1mM EDTA, 4% Trehalose, 1% Mannitol.
Storage InstructionUse a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt.

Target Information

Gene SymbolAOC3
Gene ID8639
Uniprot IDAOC3_HUMAN
ImmunogenHomo sapiens (Human)
Immunogen RegionGly27-Asn763

Additional Info

Post Translational Modifications Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue. N- and O-glycosylated.
Function Catalyzes the oxidative deamination of primary amines to the corresponding aldehydes with the concomitant production of hydrogen peroxide and ammonia. Has a preference for the primary monoamines methylamine and benzylamine. Could also act on 2-phenylethylamine but much less efficiently. At endothelial cells surface can also function as a cell adhesion protein that participates in lymphocyte extravasation and recirculation by mediating the binding of lymphocytes to peripheral lymph node vascular endothelial cells in an L-selectin-independent fashion. Isoform 2: Has no semicarbazide-sensitive amine oxidase (SSAO) activity.
Protein Name Amine Oxidase Copper-Containing 3
Amine Oxidase Copper-Containing 3
Copper Amine Oxidase
Hpao
Semicarbazide-Sensitive Amine Oxidase
Ssao
Vascular Adhesion Protein 1
Vap-1
Database Links Reactome: R-HSA-211945
Cellular Localisation Cell Membrane
Single-Pass Type Ii Membrane Protein
Alternative Protein Names Amine Oxidase Copper-Containing 3 protein
Amine Oxidase Copper-Containing 3 protein
Copper Amine Oxidase protein
Hpao protein
Semicarbazide-Sensitive Amine Oxidase protein
Ssao protein
Vascular Adhesion Protein 1 protein
Vap-1 protein
AOC3 protein
VAP1 protein

Information sourced from Uniprot.org

Citations

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