Human AOC1/DAO protein (Recombinant) (N-His) (STJP004255)
SPECIFICATIONS
HostE.coli
ImmunogenHomo sapiens (Human)
General Information
| Short Description | Recombinant-Human AOC1/DAO-N-His protein was developed from e.coli for the region N-His. For use in research applications. |
| Applications | ELISA/Immunogen/SDS-PAGE/WB |
| Host | E.coli |
| Note | STRICTLY FOR FURTHER SCIENTIFIC RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR THERAPEUTIC APPLICATIONS. |
Product Properties
| Dilution Range | Reconstitute in sterile water for a stock solution. A copy of datasheet will be provided with the products, please refer to it for details. |
| Formulation | Lyophilized from a solution in PBS pH 7.4, 0.02% NLS, 1mM EDTA, 4% Trehalose, 1% Mannitol. |
| Storage Instruction | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8°C for frequent use. Store at-20 to-80°C for twelve months from the date of receipt. |
Target Information
| Gene Symbol | AOC1 |
| Gene ID | 26 |
| Uniprot ID | AOC1_HUMAN |
| Immunogen | Homo sapiens (Human) |
| Immunogen Region | Glu20-Trp322 |
Additional Info
| Post Translational Modifications | N-glycosylated. Topaquinone (TPQ) is generated by copper-dependent autoxidation of a specific tyrosyl residue. |
| Function | Catalyzes the oxidative deamination of primary amines to the corresponding aldehydes with the concomitant production of hydrogen peroxide and ammonia. Its preferred substrates are the diamines histamine and 1-methylhistamine and it could therefore play a role in allergic and immune responses. Has a broad specificity for diamines and can also act on cadaverine and putrescine, two products of amino acid catabolism. It could also act on polyamines, like spermidine and spermine though less efficiently, and regulate various biological processes. |
| Protein Name | Diamine Oxidase Copper-ContainingDiamine OxidaseAmiloride-Binding ProteinAmiloride-Binding Protein 1Amine Oxidase Copper Domain-Containing Protein 1HistaminaseKidney Amine OxidaseKaoKdao |
| Database Links | Reactome: R-HSA-211945Reactome: R-HSA-6798695 |
| Cellular Localisation | SecretedExtracellular SpaceCell MembranePeripheral Membrane ProteinExtracellular Side |
| Alternative Protein Names | Diamine Oxidase Copper-Containing proteinDiamine Oxidase proteinAmiloride-Binding Protein proteinAmiloride-Binding Protein 1 proteinAmine Oxidase Copper Domain-Containing Protein 1 proteinHistaminase proteinKidney Amine Oxidase proteinKao proteinKdao proteinAOC1 proteinABP proteinABP1 proteinDAO protein |
Information sourced from Uniprot.org