Function | Removes the secondary (acyloxyacyl-linked) fatty acyl chains from the lipid A region of bacterial lipopolysaccharides. By breaking down LPS, terminates the host response to bacterial infection and prevents prolonged and damaging inflammatory responses. In peritoneal macrophages, seems to be important for recovery from a state of immune tolerance following infection by Gram-negative bacteria. |
Protein Name | Acyloxyacyl Hydrolase Cleaved Into - Acyloxyacyl Hydrolase Small Subunit - Acyloxyacyl Hydrolase Large Subunit |
Cellular Localisation | SecretedCytoplasmic VesicleDetected In Urine |
Alternative Protein Names | Acyloxyacyl Hydrolase Cleaved Into - Acyloxyacyl Hydrolase Small Subunit - Acyloxyacyl Hydrolase Large Subunit proteinAOAH protein |
Information sourced from Uniprot.org