This ANXA2 Sandwich ELISA is an in-vitro enzyme-linked immunosorbent assay for the measurement of samples in human serum, plasma and other biological fluids.
Applications
ELISA
Reactivity
Human
Sensitivity
0.38ng/mL
Detection Limit
0.63~40ng/mL
Note
FOR SCIENTIFIC EDUCATIONAL RESEARCH USE ONLY (RUO). MUST NOT BE USED IN DIAGNOSTIC OR OTHER MEDICAL APPLICATIONS.
Product Properties
Storage Instruction
If unopened the kit may be stored at 2-8°C for up to 1 month. If the kit will not be used within 1 month, store the components separately, according to the component table in the manual.
This kit recognizes Human ANXA2 in samples. No significant cross-reactivity or interference between Human ANXA2 and analogues was observed.
Sample Type
Serum, plasma and other biological fluids
Additional Info
Function
Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Inhibits PCSK9-enhanced LDLR degradation, probably reduces PCSK9 protein levels via a translational mechanism but also competes with LDLR for binding with PCSK9. (Microbial infection) Binds M.pneumoniae CARDS toxin, probably serves as one receptor for this pathogen. When ANXA2 is down-regulated by siRNA, less toxin binds to human cells and less vacuolization (a symptom of M.pneumoniae infection) is seen.
Protein Name
Annexin A2Annexin IiAnnexin-2Calpactin I Heavy ChainCalpactin-1 Heavy ChainChromobindin-8Lipocortin IiPlacental Anticoagulant Protein IvPap-IvProtein IP36
SecretedExtracellular SpaceExtracellular MatrixBasement MembraneMelanosomeIn The Lamina Beneath The Plasma MembraneIdentified By Mass Spectrometry In Melanosome Fractions From Stage I To Stage IvTranslocated From The Cytoplasm To The Cell Surface Through A Golgi-Independent Mechanism
Alternative ELISA Names
Annexin A2 ELISA kitAnnexin Ii ELISA kitAnnexin-2 ELISA kitCalpactin I Heavy Chain ELISA kitCalpactin-1 Heavy Chain ELISA kitChromobindin-8 ELISA kitLipocortin Ii ELISA kitPlacental Anticoagulant Protein Iv ELISA kitPap-Iv ELISA kitProtein I ELISA kitP36 ELISA kitANXA2 ELISA kitANX2 ELISA kitANX2L4 ELISA kitCAL1H ELISA kitLPC2D ELISA kit
Specificity
This kit recognizes Human ANXA2 in samples. No significant cross-reactivity or interference between Human ANXA2 and analogues was observed.
